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Corey Smith headshot


Assistant Professor
QEII Foundation Scholar in Retina Research
Department of Ophthalmology and Visual Sciences, Dalhousie University

Affiliate Scientist
Nova Scotia Health

Dedicated to conducting research in a collaborative and innovative environment with the goal improving patient care through better understanding of retinal eye diseases.


Address :
Department of Ophthalmology & Visual Sciences
QEII Health Sciences Centre
2035-2 West Victoria, 1276 South Park St.
Halifax, Nova Scotia, Canada B3H 2Y9

Phone : (902) 473-3491         Email : corey.smith@dal.ca


The goal of my research program is to provide new insight into retinal diseases using ophthalmic imaging. Specifically, I use innovative acquisition and processing methods to obtain and extract new information from imaging data. This field of research is important to ensure imaging devices are used to the best of their potential for improved patient care when diagnosing, treating, and monitoring retinal diseases. Two important priorities for my research program are:

  1. Creating a diverse research group with multi-disciplinary collaborations
  2. Research that is a balance of experimental methods and clinical relevance

Retinal Imaging

Symbol of an eye

The eye is a complex organ that contains central nervous system tissue, but also remarkably accessible to view and study non-invasively.

Image Interpretation

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Novel methods for image analysis, especially 3D data, can provide new understanding of retinal diseases and be used for artificial intelligence.

Clinical Data

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Answering research questions with a combination of administrative and clinical records from hospital databases and chart reviews.

Research Opportunities: Trainees/students interested in research opportunities should send a summary of their interests and their CV to corey.smith@dal.ca. We will work with trainees to develop strong proposals for scholarship and fellowship applications.


Emma-Lee Rhyno

Research Assistant

Simone Alim

Research Assistant

Jaide Cashin

Medical Sciences Honours Student


Di Pierdomenico J, Henderson DCM, Giammaria S, Smith VL, Jamet AJ, Smith CA, Hooper ML, Chauhan BC. Age and intraocular pressure in murine experimental glaucoma. Prog Ret Eye Res In Press. https://doi.org/10.1016/j.preteyeres.2021.101021

Hirasawa K, Smith CA, West ME, Sharpe GP, Shuba LM, Rafuse PE, Nicolela MT, Vianna JR, Chauhan BC. Discrepancy in loss of macular perfusion density and ganglion cell thickness in early glaucoma. Am J Ophthalmol 2021;221:39-47. https://doi.org/10.1016/j.ajo.2020.08.031

Duggan E, Smith CA, Hooper ML, Chauhan BC. Colocalization of optical coherence tomography angiography with histology in the mouse retina. Microvasc Res; Published Online First: 8 August 2020. https://doi.org/10.1016/j.mvr.2020.104055

Hanna V, Sharpe GP, West ME, Hutchison DM, Shuba LM, Rafuse PE, Nicolela MT, Smith CA, Chauhan BC. Peripapillary retinal segmentation in optical coherence tomography angiography. Ophthalmology 2020;127(12):1770-1772. https://doi.org/10.1016/j.ophtha.2020.05.032

Smith CA, West ME, Sharpe GP, Hutchison DM, Shuba LM, Rafuse PE, Nicolela MT, Chauhan BC. Asymmetry analysis of macular optical coherence tomography angiography in patients with glaucoma and healthy subjects. Br J Ophthalmol 2020;104(12):1724-1729. http://dx.doi.org/10.1136/bjophthalmol-2019-315592

Smith CA, Hooper ML, Chauhan BC. Optical coherence tomography angiography in mice: Quantitative analysis after experimental models of retinal damage. Invest Ophthalmol Vis Sci 2019;60(5):1556-1565. https://doi.org/10.1167/iovs.18-26441  PDF Document Icon

Smith CA, Chauhan BC. In vivo imaging of adeno-associated viral vector labelled retinal ganglion cells. Sci Rep 2018;8:1490. http://dx.doi.org/10.1038/s41598-018-19969-9  PDF Document Icon

Smith CA, Vianna JR, Chauhan BC. Assessing retinal ganglion cell damage. Eye 2017;31(2):209-217. https://dx.doi.org/10.1038/eye.2016.295  PDF Document Icon

Smith CA, Chauhan BC. Imaging retinal ganglion cells: Enabling experimental technology for clinical application. Prog Retin Eye Res 2015;44:1-14. http://dx.doi.org/10.1016/j.preteyeres.2014.10.003

Smith CA, Newson TA, Hutnik CML, Hill KA. Identification of anomalous features of intravitreal injections using micro-computed tomography. Curr Eye Res 2013;38:375-380. http://dx.doi.org/10.3109/02713683.2012.744059

Smith CA, Newson TA, Leonard KC, Barfett J, Holdsworth DW, Hutnik CML, Hill KA. A novel framework for modeling ocular drug transport and flow through the eye using micro-CT. Phys Med Biol 2012;57(19):6295-6307. http://dx.doi.org/10.1088/0031-9155/57/19/6295

Click here to view PubMed entries for Corey A. Smith


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